Exercise-induced bronchospasm, a complementary tool on asthma evaluation
Main Article Content
Abstract
Introduction: Bronchial challenge with exercise is used to identify and characterize airway hyperresponsiveness. Bronchoconstriction induced by exercise can occur both on asthmatic and non-asthmatic infant patients. Objective: Characterization of Pediatric patients submitted to exercise challenge. Additionally, we tried to test whether the risk of exercise-induced bronchoconstriction in children increases if the patient has asthma or is obese. Methods: Retrospective study (2014-2019) of patients submitted to exercise challenge in a Pulmonary Department of a district hospital. Demographic and clinical data, allergic status, respiratory function, exercise challenge were collected and analyzed. The test was carried out on a treadmill, positive when falling > 10%. Results: Thirty-three patients were examined. 48% of patients were female. Mean age of 13,97 ± 4,48 years. Mean Body Mass Index of 20,2 kg/m2. The test was positive on 42% (n=14) and within these 9 had diagnosis of asthma and rhinitis, 4 of asthma and 1 rhinitis. For the patients with a positive result on the test, their mean body mass index was superior (21.57 kg / m2 against 20.22 kg / m2), however the difference had no statistically significance (p = 0,26). Conclusion: No significant difference occurred in exercise-induced bronchoconstriction between obese or non-obese children. Nevertheless, there was a difference in asthmatics and non-asthmatics patients. Most patients with positive result on the test were asthmatic. The author intends to demonstrate the importance of this test as a complementary tool on evaluating asthmatic patients.
Downloads
Article Details

This work is licensed under a Creative Commons Attribution 4.0 International License.
References
1. Couto, Mariana; Jacinto, Tiago. Avaliação objetiva no diagnóstico de broncoconstrição induzida pelo exercício. Rev Port Imunoalergologia, Lisboa. 2019;27(4):304-325.
2. McFadden ER, Gilbert IA. Exercise induced asthma. N Engl J Med. 1994;330:1362-1367.
3. Anderson SD, Daviskas E. The mechanism of exercise-induced asthma J Allergy Clin Immunol. 2000;106:453-459.
4. Stickland MK, Rowe BH, Spooner CH, Vandermeer B, Dryden DM. Effect of warm-up exercise on exercise-induced bronchoconstriction. Med Sci Sports Exerc. 2012;44(3):383-91.
5. Silva, L., Silva, P., Silva, M. and Cheik, N.. Avaliação dos fatores de risco associados ao broncoespasmo induzido pelo exercício em crianças e adolescentes sem diagnóstico prévio de asma. Arquivos de Asma, Alergia e Imunologia. 2017;1(4).
6. Randolf C. An Update on Exercise-Induced Bronchoconstriction With and Without Asthma. Current Allergy and Asthma Reports. 2009;9:433-438.
7. Weiler JM, Brannan JD, Randolph CC, Hallstrand TS, Parsons J, Silvers W, et al. Exercise-induced bronchoconstriction update-2016. J Allergy Clin Immunol. 2016;138:1292-5.e36.
8. Global Strategy for asthma Management and Prevention. GINA Report; 2019.
9. Parsons JP, Hallstrand TS, Mastronarde JG, Kaminsky DA, Rundell KW, Hull JH, et al. An official American Thoracic Society clinical practice guideline: exercise-induced bronchoconstriction. Am J Respir Crit Care Med. 2013;187:1016-27.
10. Weiler JM, Brannan JD, Randolph CC, Hallstrand TS, Parsons J, Silvers W, et al. Exercise-induced bronchoconstriction update-2016. J Allergy Clin Immunol. 2016;138:1292-5.10.1016
11. Leite, N.; Radomisnski, R.B.; Lopes, W.A. et al. Prevalência de asma induzida pelo exercício em asmáticos e não-asmáticos, obesos e não-obesos. Arquivo Brasileiro de Endocrinologia e Metabologia. 2004;48(5).
12. Lødrup Carlsen KC, Håland G, Devulapalli CS, Munthe-Kaas M, Pettersen M, Granum B, et al. Asthma in every fifth child in Oslo, Norway: a 10-year follow up of a birth cohort study. Allergy;2006.
13. Kawabori, I.; Pierson, W. E.; Conquest, L. L. et al. Incidence of exercise induced asthma in children. Journal Allergy Clinical Immunology.1976;58:447.
14. Price, J. F.; Cogswell, J. J.; Joseph, M. C. et al. Exercise-induced bronchoconstriction, skin sensitivity, and serum IgE in children with eczema. Arch Dis Child. 1976;51:912-917.
15. Kaplan, t. A.; Montana, E. Exercise-induced bronchospam in nonasthmatic obese children. Clinical Pediatrics (Phila). 1993;32(4):220-5.
16. Gokbel, H.; Atas, S. Exercise-induced bronchospam in nonasthmatic obese and nonobese boys. Journal Sports Medicine Physical Fitness. 1999;39(4):361-4.
17. Van Veen WJ, Driessen JMM, Kersten ETG, et al. BMI predicts exercise induced bronchoconstriction in asthmatic boys. Pediatr Pulmonol. 2017;52(9):1130-1134.