Eficácia e segurança do Lactobacillus reuteri DSM 17938 nas patologias infantis - Revisão sistemática de estudos randomizados e controlados
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Introdução: Probióticos são definidos como micro-organismos vivos que, administrados em quantidades adequadas, conferem benefícios à saúde do hospedeiro. O Lactobacillus reuteri DSM 17938 tem sido amplamente estudado, especialmente em crianças. Objetivo: Diante da grande quantidade de publicações que avaliaram essa cepa probiótica, e o interesse na avaliação dos dados de segurança disponíveis nos estudos, considerou-se válida a realização de uma revisão sistemática atual, avaliando os dados referentes a utilização do Lactobacillus reuteri DSM 17938 nessa população. Fontes de dados: Em março de 2018 foi realizada busca na literatura com objetivo de localizar RCTs ou revisões sistemáticas desses estudos, já publicados e indexados, realizados em crianças de 0 a 18 anos, avaliando a eficácia do Lactobacillus reuteri DSM 17938 administrado por via oral. Síntese dos dados e conclusões: Ficou demonstrado que o L. reuteri DSM 17938 possui evidência científica suficiente para ser recomendado na cólica do lactente e diarreia aguda. Na dor abdominal funcional e intolerância alimentar os dados apontam para um efeito benéfico dessa cepa, sendo necessários mais estudos clínicos nas mesmas afecções e população. Já na diarreia nosocomial, os dados dos artigos, não indicam que haja benefício da cepa quando utilizada em crianças.
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