Leite materno: um alimento probiótico

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Gabriela Ricci Meneguetti
Bruna Almeida Silva
Mariella Vieira Pereira Leão

Resumo

Introdução: Sabe-se que o leite materno é o alimento essencial ao recém-nascido até, pelo menos, seus seis meses de vida. Dentre outras substâncias, o leite materno apresenta microrganismos, que quando presentes em quantidades adequadas, conferem benefícios à saúde do bebê. Objetivos: Correlacionar a presença de microrganismos no leite materno com os benefícios à saúde do recém-nascido/lactente, atribuindo características probióticas a esse alimento. Metodologia: Assim, o presente trabalho revisou a literatura, selecionando trabalhos disponíveis na plataforma PubMed que explorassem a composição e os benefícios desse alimento, bem como suas propriedades probióticas. Síntese de dados: Observou-se que os gêneros de bactérias Lactobacillus e Bifidobacterium, amplamente conhecidos como probióticos, são encontrados no leite materno, e que a composição do leite influencia suas presenças. A composição, por sua vez, pode ser influenciada pelo estilo de vida materno, incluindo a incidência de psicopatologias como depressão, ansiedade e estresse. Conclusão: Concluiu-se que, incontestavelmente, o leite materno pode ser considerado um alimento probiótico, com a vantagem do fácil acesso e nenhum custo, tornando-se a melhor alternativa para nutrir e promover a saúde do recém-nascido.

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Ricci Meneguetti , G., Almeida Silva , B., & Vieira Pereira Leão , M. (2024). Leite materno: um alimento probiótico. Revista De Pediatria SOPERJ, 25(1), e20250319 . https://doi.org/10.31365/issn.2595-1769.v25i1p21-26
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Referências

1. Brasil. Ministério da Saúde. Saúde da Criança: Nutrição Infantil [Internet]. 2009. https://bvsms.saude.gov.br/bvs/publicacoes/saude_crianca_nutricao_aleitamento_alimentacao.pdf

2. Andreas NJ, Kampmann B, Mehring Le-Doare K. Human breast milk: A review on its composition and bioactivity. Early Human Development [Internet]. 2015 Nov;91(11):629-35. https://www.sciencedirect.com/science/article/pii/S0378378215001772

3. Barbosa S, Nunes L. [cited 2024 Feb 24]. https://estudogeral.uc.pt/bitstream/10316/88924/1/M_Sara%20Nunes.pdf

4. Lozupone CA, Stombaugh JI, Gordon JI, Jansson JK, Knight R. Diversity, stability and resilience of the human gut microbiota. Nature [Internet]. 2012 Sep 13;489(7415):220-30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577372/

5. Pariente N. A field is born. Nature Research [Internet]. 2019 Jun 17. https://www.nature.com/articles/d42859-019-00006-2

6. Dominguez-Bello MG, Godoy-Vitorino F, Knight R, Blaser MJ. Role of the microbiome in human development. Gut [Internet]. 2019 Jan 22 [cited 2019 Nov 7];68(6):1108-14. https://gut.bmj.com/content/68/6/1108

7. Bode L, McGuire M, Rodriguez JM, Geddes DT, Hassiotou F, Hartmann PE, et al. It’s alive: microbes and cells in human milk and their potential benefits to mother and infant. Advances in Nutrition (Bethesda, Md) [Internet]. 2014 Sep 1;5(5):571-3. https://pubmed.ncbi.nlm.nih.gov/25469400/

8. Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature reviews Gastroenterology & hepatology [Internet]. 2014;11(8):506-14. https://www.nature.com/articles/nrgastro.2014.66

9. Yousefi B, Eslami M, Ghasemian A, Kokhaei P, Salek Farrokhi A, Darabi N. Probiotics importance and their immunomodulatory properties. Journal of Cellular Physiology. 2018 Oct 14;234(6):8008-18.

10. Lara-Villoslada F, Olivares M, Sierra S, Miguel Rodríguez J, Boza J, Xaus J. Beneficial effects of probiotic bacteria isolated from breast milk. British Journal of Nutrition. 2007 Oct;98(S1):S96-100.

11. Krol KM, Grossmann T. Psychological effects of breastfeeding on children and mothers. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 2018 Jun 22;61(8):977-85.

12. Smith KA. Louis Pasteur, the father of immunology? Frontiers in Immunology [Internet]. 2012 Apr 10;3(68). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342039/

13. Vandenplas Y, Huys G, Daube G. Probiotics: an update. Jornal de Pediatria. 2015 Jan;91(1):6-21.

14. Wieërs G, Belkhir L, Enaud R, Leclercq S, Philippart de Foy JM, Dequenne I, et al. How Probiotics Affect the Microbiota. Frontiers in Cellular and Infection Microbiology. 2020 Jan 15;9(454).

15. Suez J, Zmora N, Segal E, Elinav E. The pros, cons, and many unknowns of probiotics. Nature Medicine. 2019 May 6;25:716-29.

16. Marco ML, Pavan S, Kleerebezem M. Towards understanding molecular modes of probiotic action. Current Opinion in Biotechnology. 2006 Apr;17(2):204-10.

17. Guo Q, Goldenberg JZ, Humphrey C, El Dib R, Johnston BC. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database of Systematic Reviews. 2019 Apr 30;(4).

18. Goldenberg JZ, Yap C, Lytvyn L, Lo CKF, Beardsley J, Mertz D, et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database of Systematic Reviews. 2017 Dec 19;12(12).

19. Kumar S, Singhi S. Role of probiotics in prevention of Candida infection in critically ill children. Mycoses. 2012 Nov 26;56(3):204-11.

20. Leão MVP, Tavares TAA, Gonçalves E Silva CR, Dos Santos SSF, Junqueira JC, de Oliveira LD, et al. Lactobacillus rhamnosus intake can prevent the development of Candidiasis. Clinical Oral Investigations [Internet]. 2018 Sep 1 [cited 2024 Feb 24];22(7):2511-8. https://pubmed.ncbi.nlm.nih.gov/29372447/

21. Oliveira V, Soléo S, Silva CRG, Olavo A, Vieira M. Lactobacillusis able to alter the virulence and the sensitivity profile ofCandida albicans. Journal of Applied Microbiology. 2016 Oct 24;121(6):1737-44.

22. Xie HY, Feng D, Wei DM, Mei L, Chen H, Wang X, et al. Probiotics for vulvovaginal candidiasis in non‐pregnant women. The Cochrane Database of Systematic Reviews [Internet]. 2017 Nov 23;2017(11). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486023/

23. Xue L, He J, Gao N, Lu X, Li M, Wu X, et al. Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia. Scientific Reports. 2017 Mar 28;7(1).

24. Azad MdAK, Sarker M, Li T, Yin J. Probiotic Species in the Modulation of Gut Microbiota: An Overview. BioMed Research International [Internet]. 2018;2018:1-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964481/

25. Liu G, Ren W, Fang J, Hu CAA, Guan G, Al-Dhabi NA, et al. l-Glutamine and l-arginine protect against enterotoxigenic Escherichia coli infection via intestinal innate immunity in mice. Amino Acids [Internet]. 2017 Mar 15 [cited 2019 Oct 31];49(12):1945-54. https://link.springer.com/article/10.1007%2Fs00726-017-2410-9

26. Yu L, Zhao X, Cheng M, Yang G, Wang B, Liu H, et al. Saccharomyces boulardii Administration Changes Gut Microbiota and Attenuates D-Galactosamine-Induced Liver Injury. Scientific Reports. 2017 May 2;7(1).

27. Del Ciampo L, Del Ciampo I. Breastfeeding and the Benefits of Lactation for Women’s Health. Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics. 2018 Jun;40(06):354-9.

28. Palmeira P, Carneiro-Sampaio M. Immunology of breast milk. Revista da Associação Médica Brasileira [Internet]. 2016 Sep;62(6):584-93. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000600584

29. Li Y, Ren L, Wang Y, Li J, Zhou Q, Peng C, et al. The Effect of Breast Milk Microbiota on the Composition of Infant Gut Microbiota: A Cohort Study. Nutrients. 2022 Dec 19;14(24):5397.

30. Barclay AR, Russell RK, Wilson ML, Gilmour WH, Satsangi J, Wilson DC. Systematic Review: The Role of Breastfeeding in the Development of Pediatric Inflammatory Bowel Disease. The Journal of Pediatrics [Internet]. 2009 Sep 1 [cited 2021 Dec 16];155(3):421-6. https://www.sciencedirect.com/science/article/pii/S0022347609002376?casa_token=TqLSGDDhCrkAAAAA:cGhWxUSWLKlSc_lpD0ouU1tG2Ka7DEHtBC_54sZn03bLRCZOqjN7Ct5f4DN1KI5Pbv9fmbwFkw

31. Pereira PF, Alfenas R de CG, Araújo RMA. Does breastfeeding influence the risk of developing diabetes mellitus in children? A review of current evidence. Jornal de Pediatria. 2014 Jan;90(1):7-15.

32. Verhasselt V. Neonatal tolerance under breastfeeding influence. Current Opinion in Immunology. 2010 Oct;22(5):623-30.

33. Miles EA, Childs CE, Calder PC. Long-Chain Polyunsaturated Fatty Acids (LCPUFAs) and the Developing Immune System: A Narrative Review. Nutrients. 2021 Jan 16;13(1):247.

34. Zimmermann P, Curtis N. Breast milk microbiota: A review of the factors that influence composition. Journal of Infection. 2020 Jul;81(1):17-47.

35. Moossavi S, Sepehri S, Robertson B, Bode L, Goruk S, Field CJ, et al. Composition and Variation of the Human Milk Microbiota Are Influenced by Maternal and Early-Life Factors. Cell Host & Microbe. 2019 Feb;25(2):324-335.e4.

36. Stewart CJ, Ajami NJ, O’Brien JL, Hutchinson DS, Smith DP, Wong MC, et al. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature [Internet]. 2018 Oct;562(7728):583-8. https://www.nature.com/articles/s41586-018-0617-x

37. Ogbo FA, Okoro A, Olusanya BO, Olusanya J, Ifegwu IK, Awosemo AO, et al. Diarrhoea deaths and disability-adjusted life years attributable to suboptimal breastfeeding practices in Nigeria: findings from the global burden of disease study 2016. International Breastfeeding Journal. 2019 Jan 9;14(1).

38. Del Ciampo L, Del Ciampo I. Breastfeeding and the Benefits of Lactation for Women’s Health. Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics. 2018 Jun;40(06):354-9.

39. Gopalakrishna KP, Hand TW. Influence of Maternal Milk on the Neonatal Intestinal Microbiome. Nutrients [Internet]. 2020 Mar 20;12(3). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146310/

40. Verduci E, Giannì ML, Vizzari G, Vizzuso S, Cerasani J, Mosca F, et al. The Triad Mother-Breast Milk-Infant as Predictor of Future Health: A Narrative Review. Nutrients. 2021 Feb 2;13(2):486.

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