Systematic review of RCTs: Lactobacillus reuteri DSM 17938 in diseases of childhood
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Abstract
Introduction: Probiotics are living microorganisms, which when administered in adequate amounts, confer benefits to the health of the host. The strain Lactobacillus reuteri DSM 17938 has been extensively studied, especially in children. Objectives: In view of the large amount of publications that evaluates the probiotic strain and the interest in the evaluation of the safety data of the studies, the existence of a current systemic revision was considered, evaluating the data regarding the use of Lactobacillus. reuteri DSM 17938 in this population. Data Source: In March 2018 it was conducted a search on literature with the objective to detect randomized controlled trials or systematic reviews of these already published and indexed studies conducted in children aged 0 to 18 years, evaluating the efficacy of orally Lactobacillus reuteri DSM 17938. Data synthesis and Conclusions: It has been demonstrated that Lactobacillus reuteri DSM 17938 has sufficient scientific evidence to be recommended in infant colic and acute diarrhea. In functional abdominal pain and food intolerance, the data point to a beneficial effect of this strain, requiring more clinical studies in the same conditions and population. In nosocomial diarrhea data from the articles, do not indicate that there is benefit of the strain when used in children.
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