Clinical aspects and predictors associated with extubation failures in a Pediatric Intensive Care Unit

Abstract

bjective: To identify the main predictors associated with

extubation failure in infants and children electively extubated in

a pediatric intensive care unit. Method: Quantitative, crosssectional

and retrospective study of descriptive and analytical

nature. Data collection was performed from a secondary

database of the local Physical Therapy service. The study was

approved by the Research Ethics Committee of the institution.

Results: We included 78 patients, with a median age of 4.71

months, mostly males (52.6%). The extubation failure rate in

the sample studied corresponded to 21.8%, with laryngeal

stridor being the most frequent factor, recorded in 64% of the

failure cases. Conclusion: The participants who used the

Synchronized Intermittent Mandatory Ventilation modality

presented a significantly higher frequency of extubation failure

when compared to those who were ventilated in pressure

controlled ventilation (p=0.037). There was no statistical

difference between the groups considering age, time of invasive

mechanical ventilation, and non-compliance with the

extubation protocol.