Congenital mediastinal tumor: a case report
Main Article Content
Abstract
Introduction: Mediastinal tumors are neoplastic masses that lodge in the mediastinal cavity. This cavity contains structures such as the heart, thymus, trachea, esophagus, aorta, lymph nodes, thyroid and parathyroid glands. In more than 60% of cases, mediastinal tumors are asymptomatic. In the pediatric age group, they present high morbidity and mortality, despite their rarity. Objective: The main objective of this study is to describe a congenital mediastinal tumor. This observational and descriptive case report study was carried out through medical record data from a tertiary hospital. Case description: Newborn patient presented discomfort at birth. Imaging exams performed subsequently demonstrated a mediastinal tumor, located in the left hemithorax. The patient underwent tumor removal surgery on the first day of hospitalization, remaining on hemodynamic support, progressing to death on the 6th day of hospitalization. Discussion: Describing a case of a rare mediastinal tumor in the neonatal period alerts us to the seriousness of well-done prenatal care. Follow-up of the study using imaging methods carried out by qualified professionals, to diagnose potentially important fetal malformations early and to have the birth in a suitable location for the necessary monitoring, can reduce neonatal morbidity and mortality. This study was ethically approved under registration number 6,146,068 and the precepts of the CARE Guideline.
Downloads
Article Details

This work is licensed under a Creative Commons Attribution 4.0 International License.
References
1. Croce CM. Oncogenes and cancer. N Engl J Med. 2008;358(5):502-11. doi: 10.1056/NEJMra072367
2. Alamo L, Beck-Popovic M, Gudinchet F, Meuli R. Congenital tumors: imaging when life just begins. Insights Imaging. 2011;2(3):297-308. doi: 10.1007/s13244-011-0073-8
3. Instituto Nacional de Câncer. Estimativa 2020: incidência de câncer no Brasil. Rio de Janeiro: INCA; 2019 [citado 2021 ago 2]. Disponível em: https://inca.gov.br/publicacoes/livros/estimativa-2020-incidencia-de-cancer-no-brasil
4. Thacker PG, Mahani MG, Heider A, Lee EY. Imaging Evaluation of Mediastinal Masses in Children and Adults: Practical Diagnostic Approach Based on A New Classification System. J Thorac Imaging. 2015 Jul;30(4):247-67. doi: 10.1097/RTI.0000000000000161
5. Chen CH, Wu KH, Chao YH, Weng DF, Chang JS, Lin CH. Clinical manifestation of pediatric mediastinal tumors: a single center experience. Medicine (Baltimore). 2019;98(32):e16732. doi: 10.1097/MD.0000000000016732
6. Liu T, Al-Kzayer LFY, Xie X, Fan H, Sarsam SN, Nakazawa Y, et al. Mediastinal lesions across the age spectrum: a clinicopathological comparison between pediatric and adult patients. Oncotarget. 2017 Apr 18;8(35):59845-59853. doi: 10.18632/oncotarget.17201
7. Kratz CP, Jongmans MC, Cavé H, Wimmer K, Behjati S, Guerrini-Rousseau L, et al. Predisposition to cancer in children and adolescents. Lancet Child Adolesc Health. 2021;5(2):142-54. doi: 10.1016/S2352-4642(20)30275-3
8. Fraga JC, Komlós M, Takamuto E, Camargo L, Contelli F, Brunetto A, et al. Tumores do mediastino em crianças. J Pneumol. 2003;29(5):253-7. doi: 10.1590/S0102-35862003000500002
9. Ranganath SH, Lee EY, Restrepo R, Eisenberg RL. Mediastinal masses in children. AJR Am J Roentgenol. 2012;198(3):W197-216. doi: 10.2214/AJR.11.7027
10. Verma S, Kalra K, Rastogi S, Sidhu HS. Clinical approach to childhood mediastinal tumors and management. Mediastinum. 2020;4:21. doi: 10.21037/med-19-82
11. Sreedher G, Tadros SS, Janitz E. Pediatric mediastinal masses. Pediatr Radiol. 2022;52(10):1855-74. doi: 10.1007/s00247-022-05409-4
12. Kesner VG, Oh SJ, Dimachkie MM, Barohn RJ. Lambert-Eaton myasthenic syndrome. Neurol Clin. 2018;36(2):379-94. doi: 10.1016/j.ncl.2018.01.008
13. Guleria P, Barwad A. Paediatric mesenchymal tumors of the mediastinum. Mediastinum. 2020;4:11. doi: 10.21037/med.2020.01.03
14. Khalatbari H, Ishak GE. Imaging of Horner syndrome in pediatrics: association with neuroblastoma. Pediatr Radiol. 2021;51(2):205-15. doi: 10.1007/s00247-020-04796-w
15. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-49. doi: 10.3322/caac.21660